Expresión de búsqueda: ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY G 
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Descriptor Inglés:   ATP Binding Cassette Transporter, Subfamily G 
Descriptor Español:   Transportador de Casetes de Unión a ATP, Subfamilia G 
Descriptor Portugués:   Subfamília G de Transportadores de Cassetes de Ligação de ATP 
Sinónimos Inglés:   ABCG Proteins
ABCG Transporters
ATP Binding Cassette Transporter, Sub Family G
ATP Binding Cassette Transporter, Sub-Family G  
Categoría:   D12.776.157.530.100.228
D12.776.395.550.020.457
D12.776.543.550.192.457
D12.776.543.585.100.228
Definición Inglés:   A subfamily of ATP binding cassette transporters that function primarily in the transport of lipids and STEROLS across the CELL MEMBRANE. They also export UREA and various drugs resulting in MULTIDRUG RESISTANCE. They are smaller than most other ATP binding cassette proteins, consisting of six transmembrane alpha helices and a distinct N-terminal cytoplasmic ATP-binding domain, and function as homo- or heterodimers with other ABCG transporters. 
Nota Histórica Inglés:   2019 (2017) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   56577 
Identificador Único:   D000070996 

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